Felipe Mergulhão

Senior Researcher and Coordinator of the Research Line: Biotechnology

Research line: Biotechnology

Academic position: Assistant Professor (FEUP)

Research position at LEPABE: Integrated member

Background: PhD in Biotechnology – Instituto Superior Técnico, Portugal

Major research topics

• Bacterial adhesion to surfaces.
• Biofilm formation and resistance.
• Recombinant protein expression.
• Biomedical, industrial and marine biofilms.
• Hydrodynamic effects on biofilms

Selected Publications

Moreira, J.M.R., R. Fulgêncio, P. Alves, I. Machado, I. Bialuch, L.F. Melo, M. Simões, and F.J. Mergulhão "Evaluation of SICAN performance for biofouling mitigation in the food industry" Food Control, (2016), 62, 201-207.

Gomes, L.C., J.M.R. Moreira, J.S. Teodósio, J.D.P. Araújo, J.M. Miranda, M. Simões, L.F. Melo, and F.J. Mergulhão "96-well microtiter plates for biofouling simulation in biomedical settings" Biofouling, (2014), 30(5), 535-546.

Moreira, J.M.R., J.D.P. Araújo, J.M. Miranda, M. Simões, L.F. Melo, and F.J. Mergulhão "The effects of surface properties on escherichia coli adhesion are modulated by shear stress "Colloids and Surfaces B: Biointerfaces", (2014), 123, 1-7.

Teodósio, J.S., F.C. Silva, J.M.R. Moreira, M. Simões, L.F. Melo, M.A. Alves, and F.J. Mergulhão "Flow cells as quasi-ideal systems for biofouling simulation of industrial piping systems" Biofouling, (2013), 29(8), 953-966.

Mergulhao, F.J.M., D.K. Summers, and G.A. Monteiro, "Recombinant protein secretion in Escherichia coli" Biotechnology Advances, (2005), 23(3), 177-202.

Selected Projects

“Study of the interactions between recombinant protein secretion and the formation and stability of biofilms” (PTDC/BIO/69002/2006) funded by Fundação para a Ciência e Tecnologia. Beginning: 39 months. Role: Principal investigator.

“Initial conditions controlling the onset of biofilms” (PTDC/EBB-BIO/104940/2008) funded by Fundação para a Ciência e Tecnologia. Beginning: 2013. Duration: 40 months. Role: Principal investigator.

 “Synthetic biology approaches to engineer therapeutic” bacteria” (PTDC/EBB-BIO/102863/2008) funded by Fundação para a Ciência e Tecnologia. Beginning: 2010. Duration: 42 months. Role: Principal investigator for FEUP's team.

“Bridging systems and synthetic biology for the development of improved microbial cell factories” (MIT-Pt/BS-BB/0082/2008) funded by Fundação para a Ciência e Tecnologia (MIT-Portugal Alliance programme). Beginning: 2009. Duration: 42 months. Role: Principal investigator for FEUP's team.

“Susclean - Sustainable Cleaning and Disinfection in Fresh-Cut Food Industries” (287514) funded by the EuropeanUnion (7th Framework Programme). Beginning: 2012. Duration: 36 months. Role: Investigator for FEUP's team.